When a Philadelphia jury awarded $2.25 billion in damages this year in a case that linked Roundup to a cable technician’s blood cancer, the verdict became the largest yet in the long-running litigation over the popular Monsanto weed killer.

Corporate parent Bayer had set aside more than $10 billion in 2020 to settle about 125,000 cases, many consolidated in California. And it won a string of nine individual lawsuits that started going to trial in 2021. But the tide changed last year when juries began handing down nine- and 10-figure awards to plaintiffs who had developed non-Hodgkin lymphoma.

“They try to show that non-Hodgkin lymphoma is just something that happens randomly,” said lawyer Tom Kline, who represented the Philadelphia plaintiff with co-counsel Jason Itkin. “(But) the arc of the scientific literature has turned against Monsanto in the past seven years.”

Thousands of cases remain, including one under way in Delaware over a South Carolina groundskeeper’s cancer death. Bayer insists the weed killer is safe, but has reformulated the version sold to consumers to remove the pesticide known as glyphosate.