The OG comic was a guy talking to a baby, saying “Hey little guy, how’s it going?” and the baby replies with gibberish. The third panel indicates a pause, and then the guy responds in the fourth panel with “yea” (which is supposed to be “yeah” and not the archaic affirmation that rhymes with “nay”). It’s like he doesn’t even know what he expected when he asked the question, and is just accepting the awkwardness and confusion.

The “Jesus Christ” variant seems to imply the stunning horror of whatever the guy sees in the second panel.