This report describes the case of a 30-year-old man with a history of prolonged occupational exposure to silica and coal dust leading to the development of Erasmus syndrome, a rare condition of silicosis associated with autoimmune disease, i.e., ...

Occupational exposure to silica and coal dust is a significant risk factor for the development of systemic sclerosis, known as Erasmus syndrome, which can progress rapidly.

Early recognition of systemic sclerosis in patients with occupational exposure can prevent severe complications through timely intervention and cessation of exposure. Detailed occupational history is critical in the differential diagnosis of systemic sclerosis, especially in young men presenting with pulmonary and skin manifestations.

Silica-associated systemic sclerosis often exhibits more severe pulmonary involvement compared to idiopathic forms, necessitating targeted diagnostic and therapeutic strategies.

Protective measures, including the use of personal protective equipment and routine health screenings in high-risk occupations, are essential to prevent silica-associated autoimmune disorders.