While there’s positive progress in LSD-assisted therapy, research into its potential therapeutic benefits has a long way to go before we can really understand its impact on the brain.

A 2016 study demonstrated that LSD has the potential to change established patterns of thought – and again flagged its potential as a treatment for depression and anxiety. Participants without a history of mental illness were given a single dose of LSD, which resulted in feelings of openness, optimism, and mood for around two weeks.

Research on LSD as a therapeutic treatment for alcohol dependency has demonstrated similar results – with individuals experiencing improved levels of optimism and positivity, as well as an increased capacity to face their problems.

One of the more promising trials was with patients facing a life-threating disease. The LSD was found to reduce anxiety associated with the anticipation of death. Patients also demonstrated an improved sense of self-assurance, relaxation, and mental strength, with the results lasting around 12 months.