DMT is not orally active unless you’re on a MAOI, which is dangerous and could potentially explain the symptoms being described. I wouldn’t trust any chocolate being sold as both psychoactive and containing DMT. You’re either getting ripped off or taking something potentially very dangerous.
That’s interesting, I have genes that basically mean I’m on a natural MAOI at all times. Should I stay away from DMT then? Is that why Salvia was such a hellish nightmare?
Definitely stay away from DMT unless you want to trip balls. You should probably be on a restricted diet too, MAO inhibition is not safe and eating things like cheese could potentially send you to the hospital. I would recommend consulting a doctor if you haven’t, literally the wrong food can be life threatening so it is really something to take seriously. Also, Salvia is inherently a hellish nightmare for most people. It’s a very weird drug that fucks with perception in such a fundamental way that it is very hard to have a good time.
Yes I am on a low tyramine diet, that is actually how I found out about my genes (migraines from tyramine lead to gene test). There are also several meds I can’t take as well. But I had never known about DMT interacting with it.
DMT does not need to be heated to be active. Ayahuasca is a tea, but the psychoactive ingredient is more than just DMT from mimosa hostilis. Let’s do a quick biochemistry lesson: the reason DMT isn’t orally active is NOT because it hasn’t been “heated”, it’s because an enzyme called monoamine oxidase in our bodies is used to break down the DMT faster than it can cross the blood-brain barrier. If the chemical compound can’t cross that barrier and make it into the brain, it has no effect.
The act of taking a monoamine oxidase inhibitor (MAOI) to prevent the enzyme from breaking the drug down makes it orally bioavailable long enough to be absorbed into the blood stream and carried to the brain. And because the enzyme used to break DMT down has now been inhibited, the effects will last much, much longer.
The fallacious logical progression of “if you can make a tea out of it, you can naturally extract it, if you can extract it, you can put it into edibles.” is so incredibly fucking dangerous. Please don’t speak with such confidence without any education behind it. People could seriously be hurt.
And just to add: Ayahuasca is not just a tea of DMT vines. It is specifically a mixture of DMT and MAOI, so it can be active - and be active for quite some time
But yeah, that’s nothing to mix in during your typical Saturday night.
Precisely, ayahuasca only actually works due to some of the synergistic alkaloids that are in the concoction. There is one, actually I think a couple (it’s been a long time since I’ve done biochemistry work), natural monoamine oxidase inhibitor in the various roots/plants that gets brewed.
Some of them are legal plant sources of DMT, and those ones are good. Of course they still advertise themselves as shroom bullshit though
DMT is not orally active unless you’re on a MAOI, which is dangerous and could potentially explain the symptoms being described. I wouldn’t trust any chocolate being sold as both psychoactive and containing DMT. You’re either getting ripped off or taking something potentially very dangerous.
That’s interesting, I have genes that basically mean I’m on a natural MAOI at all times. Should I stay away from DMT then? Is that why Salvia was such a hellish nightmare?
Definitely stay away from DMT unless you want to trip balls. You should probably be on a restricted diet too, MAO inhibition is not safe and eating things like cheese could potentially send you to the hospital. I would recommend consulting a doctor if you haven’t, literally the wrong food can be life threatening so it is really something to take seriously. Also, Salvia is inherently a hellish nightmare for most people. It’s a very weird drug that fucks with perception in such a fundamental way that it is very hard to have a good time.
Yes I am on a low tyramine diet, that is actually how I found out about my genes (migraines from tyramine lead to gene test). There are also several meds I can’t take as well. But I had never known about DMT interacting with it.
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DMT does not need to be heated to be active. Ayahuasca is a tea, but the psychoactive ingredient is more than just DMT from mimosa hostilis. Let’s do a quick biochemistry lesson: the reason DMT isn’t orally active is NOT because it hasn’t been “heated”, it’s because an enzyme called monoamine oxidase in our bodies is used to break down the DMT faster than it can cross the blood-brain barrier. If the chemical compound can’t cross that barrier and make it into the brain, it has no effect.
The act of taking a monoamine oxidase inhibitor (MAOI) to prevent the enzyme from breaking the drug down makes it orally bioavailable long enough to be absorbed into the blood stream and carried to the brain. And because the enzyme used to break DMT down has now been inhibited, the effects will last much, much longer.
The fallacious logical progression of “if you can make a tea out of it, you can naturally extract it, if you can extract it, you can put it into edibles.” is so incredibly fucking dangerous. Please don’t speak with such confidence without any education behind it. People could seriously be hurt.
And just to add: Ayahuasca is not just a tea of DMT vines. It is specifically a mixture of DMT and MAOI, so it can be active - and be active for quite some time
But yeah, that’s nothing to mix in during your typical Saturday night.
Precisely, ayahuasca only actually works due to some of the synergistic alkaloids that are in the concoction. There is one, actually I think a couple (it’s been a long time since I’ve done biochemistry work), natural monoamine oxidase inhibitor in the various roots/plants that gets brewed.
These don’t have DMT