US findings suggesting ageing is not a slow and steady process could explain spikes in health issues at certain ages

cross-posted from: https://lemmy.world/post/18671978

If you have noticed a sudden accumulation of wrinkles, aches and pains or a general sensation of having grown older almost overnight, there may be a scientific explanation. Research suggests that rather than being a slow and steady process, aging occurs in at least two accelerated bursts.

The study, which tracked thousands of different molecules in people aged 25 to 75, detected two major waves of age-related changes at around ages 44 and again at 60. The findings could explain why spikes in certain health issues including musculoskeletal problems and cardiovascular disease occur at certain ages.

“We’re not just changing gradually over time. There are some really dramatic changes,” said Prof Michael Snyder, a geneticist and director of the Center for Genomics and Personalized Medicine at Stanford University and senior author of the study.

“It turns out the mid-40s is a time of dramatic change, as is the early 60s – and that’s true no matter what class of molecules you look at.”

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  • @graeghos_714English
    9•27 days ago

    Getting T-Boned on my motorcycle when I was 62 made me real old, real fast because my mobility has been so reduced

    • @[email protected]
      3•27 days ago

      Don’t give up, even if it absolutely fucking sucks. The people who give up never get it back. If you were wild enough to ride a motorcycle, you’re wild enough to invest into yourself. Because it takes guts to buy in to yourself. It’s a lot easier to just fade. I lost my mobility for a while and I fucking gave up. It made me feel like shit, and I literally spent weeks just laying in bed not really crying but feeling absolutely morose and like I had been cheated of the joy of the rest of my life. And it was fucking brutal. But I am so much more mobile and functional now than I was even a year ago and it takes so much time, effort, pain and realistic-hope (as in you can be optimistic, but also be kind to yourself and be a realist about where you are and where you’re trying to go and you’ll be a lot happier about all the small victories along the way). You might not even realize at some point how much your regained but I hope to god you find what you need and get back to some semblance of happiness.

      As for motorcycles, I am not sure I would ride them anymore nowadays because it seems like people are so brain-dead when they drive (Is it phones?) that they intentionally seem to go for folks. But safe healing, because you deserve it and even if you don’t get where you want to - don’t sell yourself short. Because that’s when stuff starts to fall apart bit by bit and I am sure you’ve still got more to live/give =)!

      • @graeghos_714English
        1•20 days ago

        No giving up, just dealing with reality. The Dr said my foot was squished like a grape being stepped on. I’m really happy to have a foot but the toes will never work right again. Every joint in 3 toes are fractured and the first joint in the little and adjoining toe are also fractured. Some days the pain from those fractures can be a little intense especially when I try to walk too much. Some of the little bones in the foot are also out of position especially in the heel. When that’s a problem it feels like the achilles is under extreme duress but because it’s bone related I can’t stretch it out. I do most of what I did before, just with more down days now. But as I said, so thankful I have a foot and leg still after a direct T-bone on the leg. Leaning to turn away from her probably saved the leg from the initial impact as she hit the bottom of the bike which snapped me up into her which is when the foot and leg got pinched. The foot being pinched stopped me from flying initially and that’s when the foot tore everything inside, my leg mostly had frame impact damage so I could see every frame junction on my knee and leg. Almost 2 years later the visibility of the damage hasn’t changed much. The jacket armor on the elbow and shoulder were both through the kevlar and into the armor itself so 60’ of tumbling took its toll but the armor took a large sum from that toll
        https://imgur.com/tRUZRL6 is the boot I was wearing. My foot pretty much tore where the boot tore. I think I got almost 50 stitches in the foot