Puberty blockers for under-18s with gender dysphoria will be banned indefinitely across the UK except for use in clinical trials, the government has announced.

Wes Streeting, the health secretary, said that after receiving advice from medical experts, he would make existing emergency measures banning the sale and supply of puberty blockers indefinite.

The Department of Health and Social Care said the Commission on Human Medicines (CHM) had published independent expert advice that there was “currently an unacceptable safety risk in the continued prescription of puberty blockers to children”.