Harvard researchers have found that M. morganii may contribute to depression by producing an inflammatory molecule.
- Biochemical analyses reveal how the gut bacterium Morganella morganii may contribute to some cases of major depressive disorder.
- The bacterium incorporates an environmental contaminant into one of its molecules, triggering inflammation — a known factor in disease development.
- These findings suggest the contaminant could serve as a biomarker and further support the idea that major depressive disorder may have autoimmune connections.
M. Morganii is not at fault here. It’s a contaminant, DEA (diethanolamine). Good old Morgan, a normal dweller among healthy gut microbiome, only mistakes the molecules of this bitch for sugar alcohol and incorporates them in the substance it produces triggering a response in the immune system. It’s all in the article.
How is it not at fault when it says its making it instead of the sugar alcohol? Its the supply for the DEA in the gut.
No, the DEA is a contaminant coming from out of the organism— it’s used in many industrial processes from the oil industry to production of many consumer products, lots of them things you put on your body like soaps, cosmetics, conditioner… The contaminant molecules just happen to fit in the gap of other substance molecules and take their place, they aren’t synthesized by the bacteria.
I don’t understand the faulty product line and such then:
“Future research will be needed to confirm this faulty product of M. morganii as a definitive cause of major depressive disorder and to gauge what percentage of cases it may be responsible for.”