It depends on what you start with. If you look at etoh tinctures you can get a lot of THC into a little amount of etoh if that’s what you want. If you are making your own with flower have fun experimenting and finding what works right for you. Otherwise, determine the potency you want, get some concentrate and dissolve it into the bottle until you get your dosage where you want it. As a reminder,you’ll need to decarb any flower you use and any wax if not using RSO.