Hey Lemmy friends. I have been on 75mg of Zoloft (sertraline) for 2 years and I recently asked if something could be done about my lower libido. The doctor added Wellbutrin (bupropin). I started off with 100mg SR, and then my doctor switched me to 150mg XR. I have noticed a rise in anxiety over the past few weeks. He originally wanted me to reduce my sertraline (Zoloft) dose, but as my anxiety increased, I decided to go back to 75mg. (Dr. told me I should increase if I felt the need). It has been a little over 2 weeks and yesterday was the first day I felt my anxiety symptoms start to go back down.

I’m considering asking if I can increase my Zoloft (sertraline) dose to 100mg XR to see if that is the “magic” combination as I feel like the Zoloft could use a boost. (Have been thinking this for months now)

Anyway, I wanted to see if there are other Lemmy folks out there who take this combo and how things are going.

  • @Fosheze
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    51 year ago

    So I’ve never tried sertraline but I am on Bupropion for my depression. My experience with that has always been that the Bupropion is basically a magic bullet when it comes to my depression but it gives me weapons grade anxiety. Personally I found that Buspirone in combination with the Bupropion worked really well. The Buspirone on it’s own doesn’t touch my depression but it does fix the anxiety cause by Bupropion. I’ve never had any sexual side effects from either medication. In fact I didn’t even get any start up sideffects from the Buspirone at all which is weird for me because normally I get really bad start up sideffects.