Global heat deaths are projected to increase by 370% if action is not taken to limit the effects of global warming, according to a study published Tuesday in The Lancet, a medical journal.

If average global temperatures reach 2 degrees Celsius above pre-industrial levels — as is expected without drastic action — an additional 524.9 million people are also expected to experience food insecurity, aggravating the global risk of malnutrition.

The study, The Lancet Countdown, is in its eighth iteration and draws on the expertise of 114 scientists and health practitioners from 52 research institutions and U.N. agencies worldwide. It found that human-caused climate change is making health-threatening temperatures more frequent, especially in the U.S.