I know a few doctors, and they all hate drug commercials (as well as webMD) because patients come in with their self-diagnosis trying to order drugs like it’s a friggin restaurant. One of them told me that even when she clearly informs them that’s not how this works, they regularly get pissed off as she continues to tell them no and doesn’t budge. She also said she knows other less stubborn or principled doctors that give into the pressure, which is exactly how big pharmaceutical companies like it.

It’s obviously working. These companies aren’t spending millions of $ on advertising just to have 0 ROI.

I think you’re probably right here, but just want to say that I’ve personally I’ve worked in multiple companies where they’ve spent millions on different things with no ROI. So it definitely happens. Sometimes leaders just like an idea and want to spend money on it.