I have had Google as an app disabled for the past 2 months. I don’t use google assistant or anything like that and I have had no issues. I’m not going to uninstall the play store, google play services or carrier services since I know those are pretty much integral to my phone.

I’ve used ADB to uninstall the vast majority of the bloatware or other software on my Samsung phone, but I’m not sure if uninstalling Google will actually cause my device to become inoperable.