• Flying Squid
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    69 months ago

    What is the advantage of this over an epi pen? The article doesn’t really say.

    • @[email protected]
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      149 months ago

      There’s an NPR article Here

      The TL;DR is

      The medication is not intended for use during an allergic reaction. Instead, it is designed to be taken repeatedly every few weeks to help reduce the risk of reactions over time. The FDA said people taking the drug should continue to avoid foods they are allergic to.

      So it seems to be along the lines of the pre exposure desensitization regimens.

      • @Evilcoleslaw
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        49 months ago

        It’s been available for a while for treatment of allergic asthma and nasal polyps. It’s a monoclonal antibody that binds with free Immunoglobulin E (IgE) antibodies that are responsible for directing allergic reactions.

    • @Fondots
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      79 months ago

      From the article

      Xolair is intended for repeated use to reduce the risk of allergic reactions and is not approved for the immediate emergency treatment of allergic reactions, including anaphylaxis.

      Epi Pens are for immediate emergency response for allergic reactions, they aren’t preventative in any way.

      Epi Pens are basically just a shot of adrenaline, they don’t actually act directly on your immune system at all, it’s basically just sends an override message to your body to forget about whatever else it’s doing and focus on opening up your airways, pumping blood, or whatever else you might need in order to, for example, run from a lion.

      Which buys you some time, but you’re still probably going to need some treatment or monitoring once the adrenaline wears off, and you’re probably going to feel like shit afterwards, and epinephrine isn’t without it’s own pretty significant risks and side effects.

    • @[email protected]
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      79 months ago

      Xolair is intended for repeated use to reduce the risk of allergic reactions and is not approved for the immediate emergency treatment of allergic reactions, including anaphylaxis.