How do you manage your trees? Myself, I use webtrees. The interface may be a bit “old” and the handling of media in particular could have been better, but it’s an online solution (so I have my tree available all the time), it’s open source, it’s 100% standards compliant, and the community is wonderful, so … What is your favourite programme?
I’ve switched between Legacy and RootsMagic. Both work with FamilySearch. I had to export a gedcom to import into Family Tree DNA because neither work directly with their database.