I use Arch Linux, and some apps require me to use Windows. I have tried to get Wine working, but it’s just too much of a hassle. If the only goal of my virtualization setup is to run something like Adobe apps (I’m not doing any gaming on it), will Virtualbox or virt-manager be the quick and easy choice for me? I have tried using Virtualbox, but it didn’t work due to some dkms drivers I think. I also don’t want to use QEMU by itself, as I don’t like using terminal commands and much prefer using a GUI to do things.
I recommend going with Virt-manager, it works much better than VirtualBox in my experience.
The reason for better performance is that virt-manager (KVM actually under the hood) is a type 1 hypervisor while virtualbox is a type 2 hypervisor.