There are some that manage to make it a long life with what most would have issues with (I.e. a lifetime of smoking.) A good friend died recently and he made it to what I would consider a long life. Was able to retire and stay active for years. Got diagnosed with cancer, two weeks later dead after the first chemo therapy. I’m very happy he didn’t live a much longer life - the pain that would have put him in would have been unbearable, and given how quickly he passed in guessing the cancer was fairly advanced…