In a 1991 interview with Melody Maker, Chuck D of Public Enemy explained:

‘Can’t Truss It’ is about how the corporate world of today is just a different kind of slavery. We don’t control what we create. And because of the media, we don’t control the way we think or run our lives. We’ve got to limit working for a situation that’s other than ours. We have no ownership of anything. If you don’t own business, then you don’t have jobs. White people have jobs because they have business. They have institutions that teach them how to live in America. Black people don’t have institutions that teach them how to deal with s–t. The Number One institution that teaches you how to deal is the family, but slavery f–ked that up. So the song is about the ongoing cost of the holocaust. There was a Jewish holocaust, but there’s a black holocaust that people still choose to ignore."

https://genius.com/Public-enemy-cant-truss-it-lyrics