N-acetylneuraminylgalactosylglucosylceramide b-1,4-N-acetylgalactosaminyltransferase, also known as B4GALNT1, is an enzyme that is encoded by the B4GALNT1 gene in humans. This enzyme is involved in the biosynthesis of complex carbohydrates, specifically gangliosides. Gangliosides are a type of glycosphingolipid that are abundant in the nervous system and play crucial roles in cell recognition, interaction, and signal transduction.