Erasmus syndrome is a rare entity in which silicosis may accompany systemic scleroderma was defined in 1957 by Erasmus.

In addition to silicosis, silica exposure can trigger autoimmune diseases such as scleroderma and rheumatoid arthritis.

Herein, a 41-year-old male patient, who worked in denim grinding for 3 months and was diagnosed with Erasmus syndrome, will be presented.

Here, we report a case of a 41-year-old male patient presenting with interstitial lung disease, scleroderma, and serpiginous supravenous hypermelanosis caused by silica exposure who worked in the denim grinding for a short period of three months. In order not to miss silicosis, especially in male patients diagnosed with scleroderma, silica exposure should be questioned. As stated in our case, Erasmus syndrome can develop even with short-term silica exposure.