If you have noticed a sudden accumulation of wrinkles, aches and pains or a general sensation of having grown older almost overnight, there may be a scientific explanation. Research suggests that rather than being a slow and steady process, aging occurs in at least two accelerated bursts.

The study, which tracked thousands of different molecules in people aged 25 to 75, detected two major waves of age-related changes at around ages 44 and again at 60. The findings could explain why spikes in certain health issues including musculoskeletal problems and cardiovascular disease occur at certain ages.

“We’re not just changing gradually over time. There are some really dramatic changes,” said Prof Michael Snyder, a geneticist and director of the Center for Genomics and Personalized Medicine at Stanford University and senior author of the study.

“It turns out the mid-40s is a time of dramatic change, as is the early 60s – and that’s true no matter what class of molecules you look at.”

  • @nilaus
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    1227 days ago

    Turned 44 6 months ago. Haven’t felt it yet. Guess it’s going to get rough soon…

    • @[email protected]
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      27 days ago

      One morning you’ll wake up and every bone in your body will pop simultaneously. Then while you lay there aching you’ll let out a 6 mimutes and 20 second fart that doesn’t have a happy ending.

    • @PrimeMinisterKeyes
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      27 days ago

      Yeah West in his seminal “Scale” kind of corroborates the whole story.

      It seems, though, that the molecular changes you are undergoing do not immediately translate into increased mortality, so you’re going to have several more years of - presumably - feeling well until the big drop-off starts for all of us at about 60.
      BTW, because of its wide range of topics, its solid scientific underpinnings and its excellent intellectual accessibility, this is one of two books I positively think should be taught at any school, the other one being Solé’s “Phase Transitions.”

    • @dezmdM
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      226 days ago

      Wait til you sleep wrong and wake up wondering how you threw your back our.