DUBAI, United Arab Emirates — Iran’s supreme leader said Friday that negotiations with America “are not intelligent, wise or honorable” after President Donald Trump floated nuclear talks with Tehran.

Ayatollah Ali Khamenei also suggested that “there should be no negotiations with such a government,” but stopped short of issuing a direct order not to engage with Washington.

Khamenei’s remarks upend months of signals from Tehran to the United States that it wanted to negotiate over its rapidly advancing nuclear program in exchange for the lifting of crushing economic sanctions worth billions of dollars.

Khamenei noted that Trump unilaterally withdrew from the earlier nuclear deal under which Iran drastically limited its enrichment of uranium and overall stockpile of the material, in exchange for crushing sanctions being removed.

“The Americans did not uphold their end of the deal,” Khamenei said. “The very person who is in office today tore up the agreement. He said he would, and he did.”