• cymbal_king
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    1 month ago

    If you smoke, quitting is the number one thing you can do to improve your physical and mental health. In the US you can call 1-800-QUIT-NOW or visit Lung.org for free evidence-based resources to help with quitting.

    On to the OP question, inhaling smoke of any kind exposes you to carcinogens. In tobacco smoke, the most abundant by mass is Benzo[a]pyrene, which is created by the process of burning. It is absorbed into your bloodstream in the lungs and damages DNA in every cell it touches. If the DNA damage occurs in the wrong gene, that can kick off a decades long process of more mutations that ultimately lead to uncontrolled cell grow. Inflammation, also caused by inhaling smoke, encourages cells to grow more and amplifies cancerous mutations.

    Quitting stops the exposure to new DNA damage and inflammation, but there has already been some damage done.

    Edit, adding an alcohol answer: Heavy alcohol use also takes a toll on your body. A big cause of this is that alcohol is fairly quickly metabolised into acetaldehyde by the liver. However, the acetaldehyde dehydrogenase enzyme can be limiting to detoxify the acetaldehyde. Acetaldehyde is an aldehyde, much like formaldehyde, and thus highly reactive with proteins and DNA. So it can damage those as well. Acetaldehyde is also the chemical mostly responsible for feelings of being hung over (in addition to general dehydration).