There’s drugnerd whispers on the internet that DXM (microdosed) can block or attenuate the development of tolerance to various ligands, particularly amphetamine.

Any DrugNerdz here who can explain the valudity of this conjecture or expand on it in any helpful way

  • @cheese_greaterOP
    3•1 year ago

    I just wonder what NMDA-antagonism has to do with the prevention of tolerance development in response to drug-taking of various substances.

    Edit: its my vague recollection that it involved no more than 20-60mg of the hydrobromide, typically.