New evidence confirms COVID-19 vaccines are overwhelmingly safe::More than 38 million COVID-19 vaccine doses have been administered in Ontario as of Oct. 8, with 23,002 reports of adverse reactions, an incidence of 0.06 per cent, Public Health Ontario says

  • @[email protected]
    link
    fedilink
    English
    537 months ago

    Guys the reason this study is important is because covid vaccines used revolutionary technology, they were the first to use mRNA based protein. If you remember we sequenced its genome within 40 days the making the vaccine was considerably easy. This is the main reason it took only 2 years for the vaccine to be made compared to years of development for other vaccines.

    • Match!!
      link
      fedilink
      English
      237 months ago

      It also means that, with this new vaccine technology, we can develop vaccines faster and faster

      • @WolfhoundRO
        link
        English
        67 months ago

        Let’s start the turbo-vaccine-printing-machine!

        • nickwitha_k (he/him)
          link
          fedilink
          English
          97 months ago

          Pretty sure that mRNA printers are indeed a thing. But, you’ll probably have better efficiency if you only use it for the template and use RNA-copying enzymes for the bulk of the work.

            • nickwitha_k (he/him)
              link
              fedilink
              English
              37 months ago

              I studied this stuff back in uni, is really fascinating, though, I’m more familiar with DNA amplification via Polymerase Chain Reaction (PCR).

              If you’re interested, I’ll give some details here and a link to a neat video. Effectively, there is an enzyme in our cells called DNA Polymerase. It literally scans a strand of DNA and copies it. In PCR, they use a solution of nucleotides (building blocks of DNA) and the DNA Polymerase extracted from a heat-loving microbe. The DNA to be copied (amplified) is added, and then the temperature maintained at the enzyme’s optimal temperature (higher than usual for other organisms). The solution is allowed to “stew” for a set amount of time, then, filtered to separate the DNA (lots of copies of the original) from everything else.

              A similar process can be done using an RNA polymerase (possibly modified) in order to amplify mRNA. So, once the template is printed, it gets put in the solution and RNA polymerases go brrrrrr.

              https://youtu.be/wJyUtbn0O5Y?si=Gkz8B87iY-35GvuZ