30yo male, 6’ 155lbs, Athletic

I’ve been on Vyvanse 50mg for about 6 months. It works very well for me but has my resting heart rate sitting close to 100 bpm. My unmedicated resting heart rate is 80 and has been since I was a child. So I do have a naturally high heart rate. 20 bpm increase seems reasonably normal, but if I get stressed then it spikes more and so does my blood pressure.

My doctor suggested adding guanfacine taken once a day before going to sleep as it supposedly lowers blood pressure and is used on it’s own to treat ADHD through a different mechanism.

If I could have the benefit of my vyvanse dose without the cardiovascular side effects, that would be sweet. Does anyone have experience adding guanfacine to an already effective dose of stimulants?

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    31 year ago

    I take both. I was on guanfacine prior to being on vyvanse. I didn’t notice any help with ADHD from guanfacine. I take it for a different reason. I haven’t had any issues with the combo though. I also have a high heart rate.