30yo male, 6’ 155lbs, Athletic

I’ve been on Vyvanse 50mg for about 6 months. It works very well for me but has my resting heart rate sitting close to 100 bpm. My unmedicated resting heart rate is 80 and has been since I was a child. So I do have a naturally high heart rate. 20 bpm increase seems reasonably normal, but if I get stressed then it spikes more and so does my blood pressure.

My doctor suggested adding guanfacine taken once a day before going to sleep as it supposedly lowers blood pressure and is used on it’s own to treat ADHD through a different mechanism.

If I could have the benefit of my vyvanse dose without the cardiovascular side effects, that would be sweet. Does anyone have experience adding guanfacine to an already effective dose of stimulants?

  • @[email protected]
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    31 year ago

    I take both. I was on guanfacine prior to being on vyvanse. I didn’t notice any help with ADHD from guanfacine. I take it for a different reason. I haven’t had any issues with the combo though. I also have a high heart rate.

    • DrWeevilJammer
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      31 year ago

      Seconding clonidine, especially for blood pressure. Also might want to check out ubiquinol (CoQ10).

  • @mazzpuzzled
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    21 year ago

    I’ve been on Vyvanse 50mg for a year and just added guanfacine a little over a month ago. My resting heart rate was averaging around 95 bpm on vyvanse alone, but adding guanfacine has lowered that down to about 65 bpm. Suffered from high blood pressure for years and was medicated for that too, but guanfacine has lowered that down to a reasonable range as well. It hasn’t done much for my ADHD so far, but I do feel physically better.

  • @[email protected]
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    11 year ago

    If you already have high blood pressure then it couldn’t hurt. My friend takes Guan with focalin