The disease has a consistent mark in the brain even when symptoms are absent.
  • @AbouBenAdhemEnglish
    24•13 days ago

    Neither the article nor the original paper spell this out explicitly, but I assume the link to depression has as much to do with the way the salience network expansion comes at the expense of other networks (like the cingulo-opercular and frontoparietal) as with the salience network itself. Like, you have a heightened awareness of what’s happening around you, but a reduced sense of agency or ability to react.

    • Mossy Feathers (They/Them)
      16•12 days ago

      Like, you have a heightened awareness of what’s happening around you, but a reduced sense of agency or ability to react.

      Holy shit this is exactly how I feel a lot of the time. Your sense of agency refers to your percieved ability to alter the outcome of an event, yes?

  • @reddig33
    1•12 days ago

    So is the brain rewiring at some point? Or does it get damaged? Or is it prewired and then turns on at some point? Depression is a disease, but people usually aren’t born depressed.

    • @AbouBenAdhemEnglish
      4•12 days ago

      The paper says it’s a persistent part of the brain’s development. It’s not a symptom of depression, it’s a heritable trait found in people prone to depression.