D-phenylalanine (enkephalinase inhibitor)

Interesting substance, its one of the few dextro (right-spinning optical isomer) amino acids that you can process or something.

I think its fascinating because its purportedly an endorphin reuptake enkephalinase inhibitor? or something so its potentially quasi-opioidergic. I’m not sold on the notion its legit but its definitely a provocative idea.

  • @[email protected]
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    63 hours ago

    Glutamate is good to know about.

    It’s the oldest intercellular signaling chemical in evolutionary history. Sponges use glutamate to communicate between cells, so it predates nervous systems.

    It has tons of distinct meanings in the human body’s context, but mostly it means “fight or flight”. A state of excessive glutamate signaling, sometimes referred to as a “glutamate storm”, is associated with feelings of overwhelm and panic attacks.

    It can be blocked from binding by a chemical called L-theanine, which occurs naturally in tea and can be bought in pills at supplement stores. Studies have shown that people who take L-theanine supplements experienced reduced beta wave amplitude and increased alpha wave amplitude.

    In my own experience, L-theanine pills can basically nullify the “frozen” feeling I have with procrastinating on complex work, such as homework or software development, or even just complex decision-making.

    In other words, it’s the most effective anti-procrastination substance I’ve ever encountered. This is compared with:

    • anti-anxiety meds like xanax
    • blood pressure meds like propranolol
    • more coffee
    • adderall
    • ritalin
    • cocaine
    • alcohol
    • antidepressants
    • microdosed LSD
    • microdosed psilocybin
    • pseudoephidrine
    • maca

    … all taken at once. Not recommended

  • Philo
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    23 hours ago

    As a pirate, my favorite amino acid is arrrrr-genine 😁

  • @_bcron
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    34 hours ago

    I’m going with the canned Mom ‘I love them all equally’ response because I don’t want any essential amino acid to feel scorned

  • Boozilla
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    34 hours ago

    Public schools and religious college failed me. I do not have a favorite amino acid.

  • ⚛️ Color 🎨
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    5 hours ago

    Tryptophan. It is a biochemical precursor for important neurotransmitters, vitamins and hormones such as melatonin, serotonin, and niacin. There happens to be very high concentrations of it in milk and eggs, both of which I love a lot. It can have sedating effects and make you feel chilled out!

    • @RBWells
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      127 minutes ago

      I am a fan of tryptophan!

  • @[email protected]
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    56 hours ago

    Probably plain L-phenylalanine, since it’s the precursor to phenethylamine, the body’s natural amphetamine.

  • Shadow
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    46 hours ago

    Lysine, because ingen tried to use it to control dinosaur populations.

  • Zerlyna
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    46 hours ago

    Tryptophan because it helps you be happy and sleepy.

  • @simplymath
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    254 minutes ago

    MSG because it’s delicious.