Summary

A new study links GLP-1 drugs like Ozempic to serious eye conditions, including nonarteritic anterior ischemic optic neuropathy (NAION), which can lead to blindness.

Researchers reviewed nine cases where patients developed vision problems after starting semaglutide or similar medications.

While the study does not prove causation, scientists suspect the drugs may contribute to these issues by rapidly lowering blood sugar or affecting optic nerve cells.

Experts call for more research and suggest that adjusting dosage rates might help mitigate potential risks for high-risk patients.

    • @Dkarma
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      -85 hours ago

      Then stop eating shit and run 3x a week.

      • Dharma Curious (he/him)
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        43 hours ago

        I don’t, I do, and there’s plenty of shit left over for you to go and eat, friend.

        I’ve been on restrictive diets for the better part of a decade, and I run as much as I am able to given problems with my feet, legs, and back. But go on making assumptions about people’s lives, it’s always a good look.

    • @[email protected]
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      -210 hours ago

      I mean this with all curiosity.

      Isn’t this a “stop a certain behavior and things get better” kind of thing?

      • Dharma Curious (he/him)
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        1410 hours ago

        It’s not, no. I’ve cut out basically all sugars. My A1C won’t go down. I start insulin once I get paid and can afford the prescription. So far ozempic is the only thing that has helped. It even allows me to be able to eat bread and pasta again, whereas before I had had to cut it out entirely, along with everything else that brought me any joy.

        • @[email protected]
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          9 hours ago

          Isn’t this typically a lifestyle issue and obesity related?

          Are you a type 1 diabetic?

          My ask is does a health professional not say “diet and exercise is the first line choice to solve this problem”

          It was a trick question: sat in my GPs office and we had this discussion juuuuust yesterday because I was curious about these drugs. Funny enough he said he prefers it to be kept for folks who are biologically incapable of naturally lowering their A1C as opposed to the new fad of this over diet and exercise.

          The safest way to lower your A1C is with weight loss through diet and exercise, but I suppose “wonder drugs with nebulous and unknown side effects are quicker”

          • @[email protected]
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            139 hours ago

            Just gonna be blunt and say that this is a pretty shitty misconception, like saying cancer sufferers didn’t pray hard enough or something.

            I’m T2D. I’m not going to provide my “fitness creds” (because why would you believe me anyway) but I’ll just say it’s absolutely not possible that my T2D is caused by poor diet or lack of exercise.

            T2D is caused by insulin in insufficient quality or quantity. The pancreas produces insulin. Some people just have a shitty pancreas that produces shitty insulin that doesn’t work. If you’re overweight then fatty pancreas makes it worse, but it’s not the underlying cause.

            If you have T2D you can’t store glucose effectively, it hangs around in your blood and fucks everything up. Consequently you shouldn’t consume carbohydrates which your liver covers to glucose.

            T2D is not caused by the consumption of sugar, but people with T2D cannot process sugar.

            For a newly diagnosed person with T2D, diet and exercise is indeed the first recommendation, because the meds suck and losing some weight might make smaller doses more effective.

            I, and others like me, lost the genetic lottery. I have to stick to an incredibly restrictive diet, and bullshit exercise regime, to delay the inevitable deterioration of my health. Even so I will be lucky to live to 60, and if I do ill probably have ass cancer or amputations or dead kidneys or some other fuckery.

            Honestly, stick your “diet and lifestyle” misconceptions up your jumper.

            • @RBWells
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              -16 hours ago

              It’s not a misconception just not a 100% rule.

              I have high blood pressure and can’t fix it with diet and exercise either, was underweight and a runner, now healthy weight yoga & lifting, have been vegetarian and omnivore, it doesn’t affect it at all. Drugs work so I take them. But it’s also true that people who are fat or inactive can reduce their blood pressure and blood sugar by getting in shape, it is usually a lifestyle thing.

            • @SupraMario
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              19 hours ago

              Pretty sure T2D is reversible with diet and exercise. It’s not like T1D. It absolutely is brought on by obesity.

              https://medschool.ucla.edu/news-article/can-diabetes-be-reversed

              It’s pretty well known at this point that if you have T1D your in the “need meds” camp. If you have T2D you’re in the “lose weight” camp. There’s tons of research on this and a ton of people who lose the weight and the T2D goes with it.

            • @[email protected]
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              9 hours ago

              You’re saying a lot as if it’s fact.

              There is no known cause for T2D however the overwhelming evidence points at lifestyle and diet.

              Medicine and science BOTH point at this being a disease of lifestyle, like gout. One damages their systems through abuse and overwhelming them.

              But go off. Be offended.

              I think it’s unethical to treat symptoms instead of the root issue and society normalizing diseases of lifestyle because we can potentially medicate the symptom away is gross.

              I’ll shove it all up my jumper.

                • @[email protected]
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                  -49 hours ago

                  I don’t care. I literally could not care any less if I come across as an asshole. The person I’m responding to spouted a bunch of nonsense and I replied in kind.

                  We’re having a discussion about a drug and it’s not possible to ask hard questions anonymously on the internet?

                  I get it, people are super touchy about their weight and don’t want to take ownership of their health.

                • @[email protected]
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                  7 hours ago

                  You made a claim “T2D is not caused by” and right there anyone who cares about truth should understand you’re speaking feelings not facts.

                  What causes T2D is still a mystery, but we have very good ideas and a lot of evidence backing those ideas.

                  Saying sugar doesn’t cause it when at best our understanding of T2D is that it’s a disease caused by damaging the body, with medical science pointing at excessive sugar intake being a likely causative effect (but again, no consensus) is the ignorant icing on your cake.

                  I hope you find the health you’re looking for, I’ll remain “ignorant” with my medical education. Thanks.

    • @Krazore
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      16 minutes ago

      These side effects are almost always from abuse, meaning high dosages or taking it for too prolonged of a period. You can also wreck your pancreas and make your TSH/LSH levels so low that they don’t show up on blood exams if you have a massive bolus dose. If you’re being responsible and taking it appropriately you should be fine.

  • paraphrand
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    15 hours ago

    Awww man. We can’t have magic drugs in our cyberpunk future? Hopefully they nail down what’s going on.

    • @EvacuateSoul
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      5 hours ago

      It’s a 9-person study. This is like the articles about bone density loss for these drugs (same as losing significant weight any other way, mitigated by exercise).

      These articles blow up and are widely shared due to our thirst for comeuppance, that people taking a “shortcut” will end up getting cancer someday and look like fools.

      I believe these drugs aren’t without risk and these links should be studied, but it would have to be orders of magnitude more prevalent to offset the good it’s done.

      I find the kneejerk cravings for scary downsides to be on par with Big Tobacco vape messaging or vaccine skepticism, and, at its root, I think it has some Puritanical holier-than-thou elements since the fatties didn’t suffer or risk enough.

      Edit: This isn’t directed at the scientists, rather the concern trolling on social media.

    • @[email protected]
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      810 hours ago

      Right, my thought was close, “oh no, you mean to tell me the definitely-too-good-to-be-true drug turned out to be too good to be true”? I’m shocked, shocked!

  • MudMan
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    517 hours ago

    Man, can you believe anglophones went with “eye doctors” as a thing they say with a straight face? So weird.

    • Aedis
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      16 hours ago

      Ophthalmologist is a hard word.

      Edit: also they went with “ear nose and throat doctor” instead of the word that just rolls off the tongue: otorhinolaryngologist

      • Dharma Curious (he/him)
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        314 hours ago

        My only issue with that word is I can never remember how the first g is pronounced. LarynGAWLogist it larynJAWLogist. It trips me up. Long ass words and pronunciation is not something I generally have a problem with, I had speech issues as a kid, and also had a super thick southern accent, and in my preteens I worked hard to make sure my pronunciation was on point and worked to change my accent. But that word in particular just fucks me up every time.

      • chingadera
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        15 hours ago

        Yeah so every once in awhile I’ll stutter when I’m speaking.

        I’ve never had a problem stuttering in my own head, but I just had that problem no less than 10 times reading your comment.