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Cake day: June 25th, 2023

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  • Am experiment that determines the relative amount of a given protein in a sample. It takes like 8 hours. Since it only gives relative amounts, in order to interpret any data, you need to do it multiple times on multiple proteins to determine what’s an “expected” amount and what’s an “unexpected” amount.

    It’s one of my least favorite types of experiments because of how mind-numbingly tedious it is. The only thing worse is qPCR






    1. A family owns 100k USD worth of Lego sets.

    2. Family wants to sell it. Family puts it on consignment at a store called Bricks and Minifigs. That means that the family still owns the sets, they are just selling it through the store and the store gets a commission for each sale.

    3. Through a combination of poor record keeping and legal fuckery, the sets go missing. What happened to the sets is currently up for legal debate, but the prevailing theory is that the Bricks and Minifigs corporate office engineered a hostile takeover of the store to take control of the sets, and then used the ensuing chaos as an excuse for the sets going missing.

    4. The family asks for the missing sets back, and the corporate stonewalls them and threatens legal action

    5. The family decides to get a YouTuber, Reckless Ben, involved. He goes to extraordinary lengths to try to get the missing sets back from corporate. Due to those extraordinary lengths, he was able to document significant evidence of dishonesty from corporate executives, as well as police corruption and collusion. That is to say, there is significant evidence that the corporate executives are personally commanding the police to harass Reckless Ben. Also due to the police corruption, he gets arrested multiple times.

    6. The internet gets involved. There is now a debate as to what Reckless Ben should or should not have done. One side argues that he was needlessly reckless and put himself and the family in a lot of legal trouble. The other side argues that his actions were the only thing that could have allowed the story to go viral, which in the long run was a net positive by exposing the corruption in the police department and in the company

    The reason this story is going viral is because:

    1. It’s a lot of money that was stolen. 100k isn’t small.

    2. This wasn’t some regular thief. The alleged thief is a multimillion dollar company.

    3. The company is using legal loopholes and colluding with the police to silence any reporting on this story



  • Close but not quite.

    Best translation is “I don’t want to go to work”

    Text: Kaisha ni ikitakunai

    Breakdown:

    Iku (to go) > ikitai (want to go) > ikitakunai (don’t want to go)

    In total: (To the office/workplace) (don’t want to go)

    “Didn’t have to go” might be translated as “do not have a need to go” (iku hitsuyou ga nai), so “I wish I didn’t have to go to work” might be translated as “kaisha ni iku hitsuyou ga nai to negaishimasu”

    (need to go to work) (there is not) (I pray/wish)


  • ContramuffintoShirts That Go HardNumerology
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    7 days ago

    X axis: the inappropriate to corporate axis

    Y axis: the funny to tragic axis

    6 is the inappropriate, funny number

    7 is the corporate, funny number

    9 is the inappropriate, tragic number

    11 is the corporate, tragic number

    Is my interpretation valid?


  • I have a sense of what you’re saying. So other comments have already pointed out the escape velocity, and those are true. But I think I can expand upon this a bit.

    So the weird thing about rocketry is that distances are insane. Like, whatever you think the distance is between 2 astronomical objects, the actual distance is probably at least 10 times that.

    This, coupled with the fact that there’s no friction in space, leads to a very unusual way of traveling. In space, if you want to go somewhere, you point your rocket in the direction that you want to go, fire the rocket up to get up to the correct speed, then just drift the rest of the way to your destination. The fact that you can just drift to different locations means that you don’t actually need to keep using up fuel for the entire trip. You only need to use fuel once, at the beginning to get to the right speed.

    In physics, this type of motion, where an object (a rocket in this case) drifts for most of the time, and suddenly changes direction in a relatively short span of time, is called impulse. So when we talk about rockets and how much “force” we need to get to places, what we’re really asking is how much impulse we need to get to the correct speed that’ll take us to where we want to go. Impulse is measured in what’s called delta-v, which is essentially a measure of “how much can we speed up.”

    There’s actually delta-v maps for the solar system. So if you want to go to this location, you need to spend this amount of delta-v to get up to the correct speed that’ll take you there. It’s an approximate map - you’ll need to do per-mission simulations to get the exact delta-v values - but it’s a good enough estimate for general usage. To use it, you start at your current location, then trace a path to where you want to go. And you just add up all the numbers that you see along the way.

    The escape velocity number is the delta-v required to leave Earth’s orbit (earth -> low earth orbit -> earth intercept)

    If you want to go to the moon, you do the same thing. Earth -> low earth orbit -> moon intercept -> low moon orbit -> moon


  • The implication is that there is a couple. The boyfriend wants the girlfriend to make out (and likely have intercourse) with another man. The girlfriend is hesitant, implying that this is entirely the boyfriend’s idea.

    Interpretation: the boyfriend has a cuckhold fetish.

    Application: any developer who uses Claude is cuckholding his own code





  • ContramuffintoLinkedinLunatics@sh.itjust.worksFrom AI coding to AI coding
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    1 month ago

    AI (statistical predictive models) work best when it’s designed for a specific purpose and when the model is too challenging to derive by hand. Detecting tumors is a specific purpose, and doing so manually is challenging enough that it requires specific training. It gets a pass by me.

    Predicting protein structures/drug effects: specific purpose, check. Doing it manually, yep, very challenging. Good use of AI.

    LLM chatbot: purpose is unclear. Making a non-AI-based chatbot is easy and has been done before. Verdict: useless technology


  • The word “nice” used to mean “stupid.” It derives from the Latin “nescio” (translated: “I don’t know”) and carried over into old French. At some point, it came to be associated with generosity, the assumption being that someone stupid is too innocent or naive to be selfish.

    It then got carried over into middle English, and the connotation for stupidity got dropped, making it so that the word meant “kind,” as opposed to “stupidly kind”



  • I don’t disagree with you, but it seems you’ve missed the point that I was trying to make. Yes, sure, the future has been predetermined in a deterministic universe. But if no person in that universe can ever figure out what that future is going to be, is there any practical distinction? To any entity within the universe, the future is completely unknown - the only thing that can be said for sure is that there is going to be a future. That is what I mean when I say that there can exist a practical free will in a deterministic universe

    In my eyes, any person who would feel dread over whether or not free will exists in a deterministic universe is splitting hairs over a thought experiment where all outcomes are practically equivalent


  • I do art from time to time. My philosophy towards art might be different from yours, so mileage may vary.

    I typically find that the sheer open endedness of creative art makes it hard to truly get into and put serious effort into, and it was only when I learned the proper techniques of drawing that creative art became more approachable. I think sometimes, people subconsciously get a bit of decision paralysis, and having a more structured approach to art helps you get into it more easily.

    If that sounds vaguely like you, then what could really help is to start off with some still life art. Just search on Google images random flowers, animal, objects, etc. Then spend around 15 minutes trying to recreate the image as accurately as possible. The trick is to pace yourself so that you don’t nitpick tiny details, but still spending enough time on it to get the sketch down accurately. This sort of practice helps build drawing technique, but also helps you develop an artistic sense for space and scale - skills that you can then apply to creative art to help it feel more structured