I think part of my Prodigy meme problem was I tried to encode in a bit too high a resolution (720x480). When retesting it today, I had a 49.1 MiB file, verses with a WEBP encoded at quality level 90, I got it down to 3 megabytes while still looking pretty good. I also kept having an issue with APNG white lines that I could never figure out.

Also, the WEBP was a bit larger than that - I wasn’t satisfied with FFMPEG’s default quality level of 75, so I experimented and decided on 97, getting a size of 333.8 KiB.

P.S For funzies, here’s the WEBP version of that Prodigy meme I was talking about (done in 85):