I somehow only just learned that daisy chaining all of your guitar pedals with the same power cable can cause extra noise. I don’t have that many pedals right now which is probably why I didn’t notice it.
I recognize it’s probably more important for recording than for live playback, but are isolated power supplies worth it? It’s a hefty price to pay.
It might get bad if/when your chain has both analog and digital pedals. I have more ground noise in my recorder/mixer (through the AC outlet) than on my pedal chain tho :/