I’m thinking I would go with either, “swing it, baby” or “right on, sister!”
So, like-
“Mr. Nartik, set course for Tau Alpha III. Warp six.”
“Course laid in, sir.”
“Right on, sister!”
This would be the 23rd or 24th century gender-neutral form of the word sister, obviously.
3,2,1 ACTIVATE!
This just made me realize the first 15 seconds of the Cowboy Bebop theme would be a killer way to do this. “3, 2, 1, Let’s Jam”