that’s why we had the opioid epidemic and not an opioid pandemic…
Maybe. But I think there are also just a lot of people that are not dealing with enough trauma and mental pain (pain-killers/type not specific) that their inner voice stops them from seeking it out.
My dad had a friend with brain cancer. He was in hospice many years ago and knew that I had struggled with addiction. He said he had received hydrocodone and oxycodone after surgeries before (he’d had many) but they always made him nauseous and feel like shit. Then at the end when he was in hospice they gave him a fentanyl patch. He said “MyName, WOW, I FINALLY UNDERSTAND how people can get addicted to this stuff now. This is remarkable!”
Off-topic story: shortly after he passed I was looking for ways to painlessly “catch the bus” on the internet (I’m fine now, this was many moons ago) and bawling my eyes out as I thought about my family and what I’d be putting them through. Suddenly, the piano next to me blasted as if someone had pounded 10 of the keys at once as hard as they possibly could. No pets, no other people home.
I’ve been through a lot since then and am happy to say I am doing fine now, but that’s one of those many WTF moments that turned me from a staunch materialistic atheist into a more spiritually understanding person.
That and the DMT. Only slightly riffing, DMT came way before that.
Your first example needs metabolized into an active ingredient. The second is an active ingredient.
There’s a bunch of different liver enzymes at play, and an absolute shit ton of normal variation between people.
Too much of those enzymes, and you burn through a 12 hr oxy in 6 hours, which makes people likely to abuse their own medication and can lead to life long addicts.
Too little and you get zero effect from “normal” opioids, but fentanyl, morphine, and other direct action opioids stick around for a lot longer and you have no tolerance.
Maybe. But I think there are also just a lot of people that are not dealing with enough trauma and mental pain (pain-killers/type not specific) that their inner voice stops them from seeking it out.
My dad had a friend with brain cancer. He was in hospice many years ago and knew that I had struggled with addiction. He said he had received hydrocodone and oxycodone after surgeries before (he’d had many) but they always made him nauseous and feel like shit. Then at the end when he was in hospice they gave him a fentanyl patch. He said “MyName, WOW, I FINALLY UNDERSTAND how people can get addicted to this stuff now. This is remarkable!”
Off-topic story: shortly after he passed I was looking for ways to painlessly “catch the bus” on the internet (I’m fine now, this was many moons ago) and bawling my eyes out as I thought about my family and what I’d be putting them through. Suddenly, the piano next to me blasted as if someone had pounded 10 of the keys at once as hard as they possibly could. No pets, no other people home.
I’ve been through a lot since then and am happy to say I am doing fine now, but that’s one of those many WTF moments that turned me from a staunch materialistic atheist into a more spiritually understanding person.
That and the DMT. Only slightly riffing, DMT came way before that.
There’s a convention or interpolation wirh regard to opioids/opiates such that:
Well, yeah…
Your first example needs metabolized into an active ingredient. The second is an active ingredient.
There’s a bunch of different liver enzymes at play, and an absolute shit ton of normal variation between people.
Too much of those enzymes, and you burn through a 12 hr oxy in 6 hours, which makes people likely to abuse their own medication and can lead to life long addicts.
Too little and you get zero effect from “normal” opioids, but fentanyl, morphine, and other direct action opioids stick around for a lot longer and you have no tolerance.
That’s what I’m saying:
Yes I was just sharing a side-thought while agreeing and sharing a story.