For me “How long could I get away with driving like an ABSOLUTE ASSHOLE all the time before I lost my licence or had an accident.” Speed limits, red lights, stop signs… forget them all. Every day I have to drive sensibly and obey the law because without my licence I dont have a job, and every day I see at least one person driving like an absolute moron and I wonder…

  • @[email protected]
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    522 months ago

    Isolate a bunch of babies together, with food etc, and see how they develop their own language and society.

  • Maxnmy's
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    462 months ago

    It may not be possible, but I want to gradually replace a person’s brain piece-by-piece with the same areas from other brains and see if they retain their sense of self when none of the original brain remains.

    • @[email protected]
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      92 months ago

      And keep the old pieces, in the end assemble them back together and see what the differences are

    • @[email protected]
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      92 months ago

      We can satisfy this curiosity with a fair amount of scientific evidence.

      Of course, most regions of the brain are so densely and variably interconnected that the technical difficulty of “replacing parts” precedes the ethical consideration by many, many years. But we do have a great deal of evidence for how our subjective sense of self is affected by “losing/removing parts” of the brain. Patients are often unaware of change unless evidence for it is overwhelming, and even then are adept at healing/reconciling instinctively. It appears that this is just something brains have evolved to do.

      So while the technology (and sheer artistry) required to match and “stitch” these networks is quite staggering, basically magic, it is theoretically possible that a patient could have every part replaced without recognizing any continuity errors in the chimeric stages, until one day they wake up as a completely different person.

    • @[email protected]
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      02 months ago

      How would you know if your sense of self is changing? Surely you always feel like yourself else you wouldn’t be you…?

      • @Feathercrown
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        12 months ago

        Surely you always feel like yourself

        This is disproven by considering dysphoria exists

  • konalt
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    392 months ago

    Raise a kid in a sensory deprivation chamber, with one exception: a monitor that only shows gen alpha brainrot videos. When they’re like 14 drop them off in a populated area and see what happens

    • @kava
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      302 months ago

      Realistically would just end up a developmentally stunted invalid. There was an example from some book, I don’t remember which, where there was a SE Asian woman who lived with her family and had a baby.

      The family was ashamed, so they forced the girl to keep the baby by itself in the attic. She would go to work most of the day, and come back to take care of it when home. That was the total extent of interaction and stimulation the baby got. It ended up being severely stunted and never learned to talk.

      Essentially young children need human interaction which includes warmth and constant validation, caring for, etc

      If you interrupt that in any way, you end up with a feral child who is permanently stunted.

    • atro_city
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      12 months ago

      They wouldn’t be able to walk at all because of floating in water for their entire life.

  • @masquenox
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    372 months ago

    I want to totally impoverish the 50 richest capitalists to see if they could “bootstrap” themselves out of it for real.

    Okay, so there’s nothing unethical or dangerous about that (they are capitalist parasites, not humans), but it would still be interesting to see.

  • @[email protected]
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    2 months ago

    Cyborg-like implants. I want titanium joints and UV vision and magnetic field sensors and charging my phone by laying it on my belly. Uncap each finger to reveal a small tool: screwdriver, USB key, cutting blade, etc.

    Note that none of that includes or requires a constant connection to a network/internet. I want to augment my interactions with the real world, not replace them with a virtual world.

    • AwkwardLookMonkeyPuppet
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      82 months ago

      I’ve looked forward to this most of my life, but given how things have changed, I would never do it. There’s no way these implants wouldn’t be subscription based, and spy on everything you do. Oh, you forgot to pay your enhanced eyeball subscription? Now you’re blind, motherfucker!

    • sp3ctr4l
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      Biohackers have been toying with very primitive versions of this for over a decade.

      Things like implanting RFID capsules in their hands or fingers to act as credit cards or key fobs… lots of fun infections.

      I am fairly sure the movement has basically died out since bluetooth became widespread.

      On the other hand, you can always sign up as a test subject for neuralink rofl.

  • @[email protected]
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    How far can you strip down the human body until it can’t survive anymore. Assisted feeding and breathing is okay. Adjustable room temperature too.

    Arms, Legs? Gone. Can we get rid of the skin? Probably, if the room is the right temperature? Bones? Most of them aren’t needed, are they? Some organs surely can go too.

    Basically, what is the bare minimum needed so the body and the mind still more or less work.

    • @[email protected]
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      172 months ago

      For this you don’t need a human, Can start with monkeys.

      Disclaimer: I don’t want this experiment to happen.

    • @[email protected]
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      72 months ago

      You should watch Johnny Got His Gun if you haven’t. Not quite as extreme but kind of similar theme.

          • @lemonmelon
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            “Landmine has taken my sight, taken my speech, taken my hearing…”

            I guess someone forgot to tell Metallica when they were writing the song that it wasn’t about a landmine.

            And I guess someone previously forgot to tell Dalton Trumbo when he wrote Johnny Got His Gun that it wasn’t an anti-war novel.

            And then they forgot to tell him again thirty-two years later when he directed the movie adaptation, Johnny Got His Gun.

            And then, worst of all, they forgot to tell the directors of the music video that “One” was anti-war and Johnny Got His Gun was about a landmine and that using scenes from the film in the music video wouldn’t be thematically appropriate.

            Damn, there were a lot of missteps! Good thing you set it all straight!

    • sp3ctr4l
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      So, firstly, may I suggest you check youtube for one of the now many ‘Adventures of Torso’ type videos done in Kenshi.

      But as far as keeping a ‘minimum viable’ human actually alive?

      You could remove limbs, but you would still have to have a method for them to eat and urinate and deficate.

      You… almost certainly could not remove all skin and keep someone alive for very long.

      For starters, they’d bleed to death. Secondly, the pain of existing without skin would probably literally kill them or drive them to try to kill themselves. Thirdly: Skin prevents infections, you’d have to keep them in basically a totally hermetically sealed room or container.

      Bones? A de-boned human?

      Well there’s almost certainly not a way to remove all of your spinal bones and skull without causing death or immensely serious paralysis and/or brain damage.

      Sure you could remain alive without all your limbs if you have caretakers, you can survive without your lower jaw as well… You can maybe? survive with the loss of a certain high percentage of your ribcage, but probably not with the entirety of it and your sternum removed.

      Organs? Well, brain, heart and liver are almost certainly mandatory.

      Though you can remove portions of your liver and it can still function and regrow to some extent…

      …and portions of your brain… though you’ll lose cognitive abilities, memories and basically become braindead but still technically alive at some point.

      Assuming we are just removing things and maybe hooking you up to various kinds if life support tubes and not replacing organs with some kind of mechanical or genetically engineered equivalent:

      I think you can survive without any kidneys if you are constantly on dialysis, but its far better to have at least one.

      Similarly: Lungs, you need at least one.

      You can have your stomach and intestines and bladder partially removed or reshaped, but not entirely.

      You can survive without eyes… and a gallbladder and a thymus and a spleen and an appendix and your tonsils… and your adenoids, and your sex organs, but you’re gonna need a great deal of monitoring and bloodwork and hormone balancing and what not.

    • BlueKey
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      22 months ago

      Yo, same what I was gonna to comment.

      It would be fascinating to see if we could archive a “brain in a jar” by this.
      Even more when considering that a big bunch of non-brain neurons are in the belly-area. So would it affect how we think?

    • bizarroland
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      22 months ago

      Hey! Somebody figured out the plot of the seminal sci-fi novel, “Don’t create the torment Nexus”!

  • @[email protected]
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    212 months ago

    I want to see how far you can push performance of the human body, and make the results compete against each other. All the bonkers whacky surgeries you can think of: limb lengthening, bone strengthening, replace their organs with bigger, stronger versions.

    All the drugs: hgh, steroids, any performance enhancing substance you can pump into an athlete.

    Have sports scientists raise children so that they’re born into a dedicated training regime for running or swimming.

    Then make them compete against each other in the trans-human olympics. I want to see someone do the 100m in 3 seconds, I want to see someone not have to come up for air during the freestyle, I want someone to throw a javelin 2 miles, I want bioengineered mutants doing gymnastics routines

      • @I_Has_A_Hat
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        Unit 731 was garbage science. About the only thing worthwhile that came from that was learning how better to treat hypothermia. Most of their experiments boiled down to “If we do terrible things to people, how much will they suffer?” with the answer being “A lot.”

        It doesn’t take live experiments to learn things like surgery without anesthesia is less effective, or that not treating people infected with horrible diseases causes them to die in agony.

        • Phoenixz
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          12 months ago

          For sure, unit 731 was an absolute horror show for psychopaths that were left to have fun with torture ecause they labeled it science

    • @[email protected]
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      32 months ago

      You’ve got some close competition, but I think you win the most Mengele response of the thread.

    • @Landless2029
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      12 months ago

      This sounds like something in the dystopian future where they take volunteers from “the poors” so thier families can survive if they win…

    • @DelphiaOP
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      82 months ago

      Oh, I like this one.

      Mind you Ive seen a cranky Silverback at the zoo, one with an extra gram of test and tren a day would be utterly fucking terrifying, also the roadrage would be something to behold… dibs not being the poor fucker giving it its shots.

      • AwkwardLookMonkeyPuppet
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        42 months ago

        Roid rage comes from excess estrogen production, not from testosterone. I’d assume that a managed steroid treatment for a gorilla would include estrogen blockers.

        • @DelphiaOP
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          22 months ago

          Yeah, and if you want to climb in there and take his bloods and administer the androgen blockers you are welcome to.

      • @papalonian
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        22 months ago

        Look up a shaved silverback… them mofos are scary.

        • @DelphiaOP
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          32 months ago

          Most big animals that are already properly scary with fur dont improve when shaved.

  • @[email protected]
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    172 months ago

    I’d give everyone a device that allows them to take photos of themselves and their lives, and then instantly post them online. Other people would be able to rate and comment on how well or badly they think someone is doing, based on these curated snapshots of their existence. In this experiment, people could also scroll through endless streams of these ‘highlights,’ constantly comparing their lives to others. To spice it up, I’d introduce a feature that allows people to see how many likes or comments other posts are getting, so they can feel great or miserable about themselves in real-time.

    • AwkwardLookMonkeyPuppet
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      32 months ago

      That’s fucking stupid, and you’re stupid, and you should feel bad, because you’re bad.

      Did I do it right?

    • @DelphiaOP
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      22 months ago

      Interesting twist… Its now mandatory.

  • @pdxfed
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    152 months ago

    A bit contemporary, but I’d like to have studied what it takes to break someone of illusions that were fed and forced on them externally, e.g. schooling, TV, social media and other forms of cultural imprinting and propaganda.

    We’ve all had that “what would it take to get this person to realize how far off base they are?” question, it would be fascinating, in a no-holds barred experiment testing various solutions and combinations to find out which is the most effective.

    E.g. someone believes climate change isn’t real because (x,y,z irrelevant). No amount of written evidence is effective to people who don’t understand the scientific method, so would it be videos, traveling to acutely affected places, having polar bears removed from all zoos, baseball bats on their knuckles when they make a logical fallacy?

    It would be interesting to then categorize the types of delusions or illusions and then prescribe treatment based on these results.

    • @DelphiaOP
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      52 months ago

      I think this one could be done ethically, even make a good TV show.

      • @pdxfed
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        82 months ago

        Parts of it could be done, but it would always stop at “the subject is uncomfortable”, which is the whole point of why changing someone’s mind against delusions, illusions and propaganda is hard. They don’t want to, so without some treatment experiments that would certainly not meet today’s medical and/or psychological standards, we wouldn’t get an answer to many questions.

        You could make a TV show sure, but all the wrong people would tune in.

        • @DelphiaOP
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          12 months ago

          You would need volunteers, but let them witness the experiments that disprove chemtrails or flat earth bullshit themselves and in person allow them to inspect the equipment and so on.

          See which ones of them are willing to actually take whats presented to them and see with their own eyes and re-evaluate their position.

  • Caveman
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    142 months ago

    Tons of drug tests on children to know the exact effect they have on development. Also anti-aging research to see how much you can potentially slow down aging and how the self repair mechanism of children works with respect to aging. The results could really give us a great insight into aging well and being healthy later in life.

    To clarify, I don’t want to see them done, performed, do them myself or anything adjacent because they’re deeply wrong and dangerous.

    • @Landless2029
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      12 months ago

      Isn’t the main issue in aging the limit of cell division? Cells can only divide a certain number of times.

      Maybe find some crazy ass backwards way to produce more stem cells in a person that the body delivers to key areas?

      • Caveman
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        12 months ago

        That theory is very outdated. People found out that telemeres are important but not the main driver of aging. A lot of research is Nov going on with senescent cells and epigenetics which looks more promising.

  • sp3ctr4l
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    142 months ago

    I’d like an extensive dietary breakdown of the potential benefits or harms of eating the flesh and organs of humans with net worths of over 10 million, 100 million, 1 billion, 10 billion, 100 billion dollars.

    • @Glytch
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      62 months ago

      That would need to be a wide ranging study with a very large sample size, just to be sure we get the most robust dataset we can. Better to use all of them than just a small sample.

  • AwkwardLookMonkeyPuppet
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    132 months ago

    I’ve broken traffic laws most of my life, and I still have a driver’s license. So, you can drive like a partially reasonable asshole indefinitely if you have the skill to pull it off.

    I’d like to see GMO humans. I want to see how far we can elevate our species using science. It’s completely unethical, but there it is.

    • @[email protected]
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      52 months ago

      How is that unethical? If anything i say it’s unethical to let us languish in these horrible bodies when we can work towards something better.

      • AwkwardLookMonkeyPuppet
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        42 months ago

        Most people are very opposed to eugenics and genetic modification of humans. There is infinite opportunity for unexpected disasters along the way to perfection, and it’s extremely apathetic to be okay with subjecting a sentient creature to the possible ramifications of unexpected outcomes.

        • @[email protected]
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          32 months ago

          Most people are only opposed to eugenics (as you’re using the word) because of a very narrow application. A rare few get genetic engineering and capitalism mixed up, which at least makes sense, i wouldn’t want musk choosing who gets a generic upgrade or how an augmentation is implemented.

          And i find it abhorrent that people are just fine with letting our entire species suffer the nightmare of random chance that is our bodies. Sure it’s surprisingly good for a system that only selects for whatever fucks the most, but we can and should eventually do better.

    • @DelphiaOP
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      52 months ago

      Oh I’m no saint. I set my cruise control at 10km/h over the speed limit, I punch it through orange lights and I sometimes roll through stop signs.

      I’m talking about full blown fast and furious wannabe swerving lanes, running reds and racing literally everywhere.

      • @polarpear11
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        22 months ago

        This describes my brother in law. Granted, he’s better than he used to be about 10 years ago, but he grew up in a small town, got to know all the cops pretty quickly, did a little jail time here and there but still has his license. He’s totalled many vehicles, spent some time in ICU and still drives like a bat out of hell.

    • @Landless2029
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      22 months ago

      The movie gattaca does this well. No murder or cleansing. But you can have a natural birth or IVF with the Impurities stripped out. “The best of you.”

      “Dirty” people were limited to shit like janitors and all high paying jobs would sneak a test in to filter out anyone “un-pure”

      • AwkwardLookMonkeyPuppet
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        12 months ago

        Gattica is a great movie, and a compelling story about the power of determination.

  • u/lukmly013 💾 (lemmy.sdf.org)
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    132 months ago

    It would also require centuries, so it’s not as possible, but breeding people for very specific traits and features. Whether appearance, physical strength, overall intelligence, specifically being great in mathematics, great smell, great sight.

    Basically, control the evolution by favoring very specific features and outright disallowing others (like hereditary diseases/disorders) that would be unacceptable in the mix.

    Since this requires a lot of time which I’d somehow theoretically have (I know, this wasn’t in the post, but anyway…), I’d want to try yet another thing. Breeding at the most late age possible, then continuing with that and extending it. Perhaps it would lead to increased lifespan, or at least lesser effects of aging in the far far offsprings. At least physically. These experiments don’t exactly favor mental health of the subjects.

    • @[email protected]
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      52 months ago

      We already did this unintentionally during our natural evolution. All we really got out of it were a group of humans who can run slightly faster on average, and a group of humans who can drink milk as adults without shitting themselves.

      I imagine the timeframe to get any noticable results would be in the thousands of years, even with deliberate selection for specific genes.

    • @weeeeum
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      12 months ago

      This was done to some extent, slave in early america were bred like cattle for specific traits, primarily strength and endurance for tilling fields.

  • @lath
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    132 months ago

    What happens when we reverse Earth’s rotation.

    • Quazatron
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      102 months ago

      I’m fairly certain that there’s a What If video on this by the XKCD guy, Randall Munroe.

    • @DelphiaOP
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      42 months ago

      While interesting I feel that one is more “Hilarously impractical” than anything else.

      • @Feathercrown
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        12 months ago

        I’m pretty sure an experiment that kills everyone would be considered immoral but we’d have to ask the IRB to be sure ;)